Titroléane™ is a trade names for detoxified extract of Tea Tree EO (= Essential Oil of Tea Tree).
Indeed, like most essential oils, Tea Tree EO contains allergens or precursors of allergens, irritants or toxic molecules. This is one of the main reasons why these EO are generally not recommended for children, and are generally recommended only in topical applications (external), diluted in vegetable oils. Even diluted, the HE may cause irritation or allergies (especially occupational hazard).
With its partners, Setubio developed a technology to keep only the beneficial molecules by eliminating those that can be harmful to the body. Titroléane™ thus concentrates molecules from tea tree EO with beneficial patented properties (pending registration) and without known harmful molecules.

Titroléane™ has many properties: antioxidant, immunomodulator, bactericide and viricide.
Applications in the medical sector (human or veterinary) are being investigated, conducted by Setubio alone or through partnerships with pharmaceutical industries.Applications in hygiene and cosmetics are also considered in the short term.


Histaway™ is an extract derived from a leguminous plant classified as GRAS (Generally Recognized As Safe) having antiparasitic properties, while respecting the commensal bacterial flora associated.
Target parasites are particularly the flagellate genii Histomonas Trichomonas, or Tetratrichomonas causing histomoniasis aka blackhead disease.
For veterinary and animal feeding (additive), the main concerned animals are birds, especially turkeys, and to a lesser extent the game birds (quail, partridge, pheasant ...), pigeons, or chickens.

Histaway ™ is the only active plant extract for which a beneficial effect (pest) has been demonstrated, without side effects or cytotoxicity / destruction of the intestinal flora.Histaway™ antiparasitic properties are covered by an international patent (WO2009 / 138684).
Histaway ™ supports Setuflor ™ and can be associated with it, to stimulate the growth of beneficial flora in parallel with the prevention / elimination of parasites (double benefit).


Phytogynal™ is the human counterpart of Histaway™. This extract presents antiparasitic properties against human pathogenic flagellates, more specifically Trichomonas vaginalis, the agent of human Trichomoniasis.
Trichomoniasis is the main protozoan STI (Sexually Transmitted Infection) in humans. According to the WHO (World Health Organization), 174 million people are affected worldwide.Trichomonas vaginalis is responsible for 30% of non-gonococcal urethritis. Trichomonas vaginitis represents 50% of vaginitis associated with vaginal discharge. Many studies demonstrate that the presence of this parasite that destabilizes the vaginal environment would promote fungal infections (candidiasis) and infections by certain viruses (HIV, etc.) and some cancers (cervical).

Phytogynal™ properties are subject to an international patent (WO2009 / 138684).


Setuflor ™ is a plant extract with growth stimulating properties specific of beneficial bacteria, in particular of Lactobacilli. Studies on numerous strains have demonstrated a very high specificity of action. The growth rate of bacterial flora can be increased by 30%, and 100%. These properties make it a booster of choice for biotechnology industries who want to significantly increase their biomass production. Setuflor can also be used as a stimulant of the digestive or vaginal flora, alone or in conjunction with other Setubio products (Histaway™, Phytogynal™).


This microalgal extract from the SETUBIO privately owned library has antibacterial properties specifically adapted to skin problems, particularly acne. The original mode of production and the exceptional properties of the S555 extract are covered by patent (FR2977799), and form a bioactive extract of choice for dermo-cosmetic and skin care products.